Protein manufacturing depends on time-consuming genetic engineering and in vivo expression, which is a bottleneck for purposeful research within the postgenomic period. Cell-free protein synthesis (CFPS) overcomes the limitation of in vivo protein biosynthesis by processing in vitro transcription and translation of a number of genes to proteins inside hours. We employed an automatic CFPS to concurrently synthesize proteins from 24 genes of the oomycete Pythium insidiosum (which causes the life-threatening illness pythiosis) and display screen for a diagnostic and therapeutic goal. CFPS efficiently synthesized 18 proteins (∼75% success price).
One protein, particularly, I06, was explicitly acknowledged by all pythiosis sera, however not management sera, examined. Py. insidiosum secreted a big quantity of I06. The protein structure of I06 is appropriate with the oligopeptide elicitor (OPEL) of the phylogenetically associated plant-pathogenic oomycete Phytophthora parasitica The OPEL-like I06 protein of Py. insidiosum can stimulate host antibody responses, much like the P. parasitica OPEL that triggers plant protection mechanisms. OPEL-like I06 homologs are current solely within the oomycetes.
Py. insidiosum accommodates two OPEL-like I06 homologs, however solely one of many two homologs was expressed throughout hyphal development. Twenty-nine homologs derived from 15 oomycetes could be phylogenetically divided into two teams. The OPEL-like genes would possibly happen within the widespread ancestor, earlier than independently present process gene achieve and loss throughout the oomycete speciation. In conclusion, CFPS presents a quick in vitro protein synthesis. CFPS concurrently generated a number of proteins of Py. insidiosum and facilitated the identification of the secretory OPEL-like I06 protein, a possible goal for the event of a management measure towards the pathogen.
Technical limitations of standard biotechnological strategies (i.e., genetic engineering and protein synthesis) forestall in depth purposeful research of the large quantities of genetic info out there in the present day. We employed a cell-free protein synthesis system to quickly and concurrently generate a number of proteins from genetic codes of the oomycete Pythium insidiosum, which causes the life-threatening illness referred to as pythiosis, in people and animals worldwide. We aimed to display screen for potential diagnostic and therapeutic protein targets of this pathogen. Eighteen proteins have been synthesized.
Of the 18 proteins, one was a secreted immunoreactive protein, referred to as I06, that triggered host immunity and was acknowledged explicitly by all examined sera from pythiosis sufferers. It is among the OPEL proteins; these proteins are current solely within the distinctive group of microorganisms referred to as oomycetes. Right here, we demonstrated that cell-free protein synthesis was helpful for the manufacturing of a number of proteins to facilitate purposeful research and establish a possible goal for prognosis and therapy of pythiosis.
A brand new neuropeptide insect parathyroid hormone iPTH within the crimson flour beetle Tribolium castaneum.
Within the postgenomics period, comparative genomics have superior the understanding of evolutionary processes of neuropeptidergic signaling techniques. The evolutionary origin of many neuropeptidergic signaling techniques could be traced date again to early metazoan evolution based mostly on the conserved sequences. Insect parathyroid hormone receptor (iPTHR) was beforehand described as an ortholog of vertebrate PTHR that has a well known operate in controlling bone reworking. Nonetheless, there was no sequence homologous to PTH sequence in insect genomes, leaving the iPTHR as an orphan receptor.
Right here, we recognized the genuine ligand insect PTH (iPTH) for the iPTHR. The taxonomic distribution of iPTHR, which is missing in Diptera and Lepidoptera, supplied a lead for figuring out the genuine ligand. We discovered {that a} beforehand described orphan ligand referred to as PXXXamide (the place X is any amino acid) described within the cuttlefish Sepia officinalis has an identical taxonomic distribution sample as iPTHR. Checks of this peptide, iPTH, in purposeful reporter assays confirmed the interplay of the ligand-receptor pair. Research of a mannequin beetle
Tribolium castaneum, was used to analyze the operate of the iPTH signaling system by RNA interference adopted by RNA sequencing and phenotyping. The outcomes urged that the iPTH system is probably going concerned within the regulation of cuticle formation that culminates with a phenotype of defects in wing exoskeleton maturation on the time of grownup eclosion. Furthermore, RNAi of iPTHRs additionally led to vital reductions in egg numbers and hatching charges after parental RNAi. Regardless of herculean efforts using a variety of antibiotic discovery platform methods, together with genomics, bioinformatics, techniques biology and postgenomic approaches, success has been at greatest incremental.
Antibacterial Discovery: 21st Century Challenges.
It has been practically 50 years for the reason that golden age of antibiotic discovery (1945-1975) ended; but, we nonetheless battle to establish novel drug targets and to ship new chemical lessons of antibiotics to exchange these rendered out of date by drug resistance. Clearly, discovering new lessons of antibiotics is basically onerous, so repeating the previous methods, whereas anticipating completely different outcomes, appears to boarder on madness. The important thing questions handled on this assessment embody:
 Zap 70 antibody |
|
20R-2009 |
Fitzgerald |
50 ug |
EUR 281 |
|
Description: Rabbit polyclonal Zap 70 antibody |
Zap 70 antibody |
|
20R-2010 |
Fitzgerald |
50 ug |
EUR 281 |
|
Description: Rabbit polyclonal Zap 70 antibody |
Zap 70 antibody |
|
20R-2340 |
Fitzgerald |
50 ug |
EUR 281 |
|
Description: Rabbit polyclonal Zap 70 antibody |
Zap 70 antibody |
|
20R-2341 |
Fitzgerald |
50 ug |
EUR 281 |
|
Description: Rabbit polyclonal Zap 70 antibody |
 Antibody) Tyrosine-Protein Kinase ZAP-70 (ZAP-70) Antibody |
|
abx012369-100ug |
Abbexa |
100 ug |
EUR 439 |
|
|
Tyrosine-Protein Kinase ZAP-70 (ZAP-70) Antibody |
|
abx139944-01mg |
Abbexa |
0.1 mg |
EUR 384 |
|
|
Tyrosine-Protein Kinase ZAP-70 (ZAP-70) Antibody |
|
abx140043-01mg |
Abbexa |
0.1 mg |
EUR 425 |
|
|
 ZAP-70 Polyclonal Antibody |
|
ES7532-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human/Mouse/Rat. This antibody is tested and validated for IHC, IF, WB, ELISA, WB, ELISA |
ZAP-70 Polyclonal Antibody |
|
ES7532-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human/Mouse/Rat. This antibody is tested and validated for IHC, IF, WB, ELISA, WB, ELISA |
ZAP-70 Polyclonal Antibody |
|
ES7533-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA |
ZAP-70 Polyclonal Antibody |
|
ES7533-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA |
ZAP-70 Polyclonal Antibody |
|
ES7534-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
ZAP-70 Polyclonal Antibody |
|
ES7534-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
ZAP-70 Polyclonal Antibody |
|
ES7535-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
ZAP-70 Polyclonal Antibody |
|
ES7535-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
ZAP-70 Polyclonal Antibody |
|
ES8738-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human. This antibody is tested and validated for IHC, WB, ELISA |
ZAP-70 Polyclonal Antibody |
|
ES8738-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 from Human. This antibody is tested and validated for IHC, WB, ELISA |
 Antibody) ZAP-70 (pY493) Antibody |
|
20-abx119340 |
Abbexa |
-
EUR 314.00
-
EUR 98.00
-
EUR 398.00
-
EUR 495.00
|
- 100 ug
- 10 ug
- 200 ug
- 300 µg
|
|
|
 Antibody) ZAP-70 (pY319) Antibody |
|
abx012370-100ug |
Abbexa |
100 ug |
EUR 439 |
|
|
ZAP-70 (pY493) Antibody |
|
abx012371-100ug |
Abbexa |
100 ug |
EUR 439 |
|
|
ZAP-70 Polyclonal Antibody |
|
ABP60950-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human. This ZAP-70 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human ZAP-70 protein at amino acid sequence of 391-440 |
ZAP-70 Polyclonal Antibody |
|
ABP60950-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human. This ZAP-70 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human ZAP-70 protein at amino acid sequence of 391-440 |
ZAP-70 Polyclonal Antibody |
|
ABP60950-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human. This ZAP-70 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human ZAP-70 protein at amino acid sequence of 391-440 |
ZAP-70 Polyclonal Antibody |
|
ABP56533-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse, Rat. This ZAP-70 antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y493 |
ZAP-70 Polyclonal Antibody |
|
ABP56533-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse, Rat. This ZAP-70 antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y493 |
ZAP-70 Polyclonal Antibody |
|
ABP56533-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse, Rat. This ZAP-70 antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y493 |
ZAP-70 Polyclonal Antibody |
|
ABP56534-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse. This ZAP-70 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y315 |
ZAP-70 Polyclonal Antibody |
|
ABP56534-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse. This ZAP-70 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y315 |
ZAP-70 Polyclonal Antibody |
|
ABP56534-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse. This ZAP-70 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y315 |
ZAP-70 Polyclonal Antibody |
|
ABP56535-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse, Rat. This ZAP-70 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y319 |
ZAP-70 Polyclonal Antibody |
|
ABP56535-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse, Rat. This ZAP-70 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y319 |
ZAP-70 Polyclonal Antibody |
|
ABP56535-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse, Rat. This ZAP-70 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y319 |
ZAP-70 Polyclonal Antibody |
|
ABP56536-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse. This ZAP-70 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y292 |
ZAP-70 Polyclonal Antibody |
|
ABP56536-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse. This ZAP-70 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y292 |
ZAP-70 Polyclonal Antibody |
|
ABP56536-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 from Human, Mouse. This ZAP-70 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the non-phosphorylation site of Y292 |
 Anti-ZAP-70 antibody |
|
STJ98456 |
St John's Laboratory |
100 µl |
EUR 234 |
|
Description: Mouse monoclonal to ZAP-70. |
Anti-ZAP-70 antibody |
|
STJ98801 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to ZAP-70. |
Anti-ZAP-70 antibody |
|
STJ99214 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Mouse monoclonal to ZAP-70. |
Anti-ZAP-70 antibody |
|
STJ96294 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to ZAP-70. |
Anti-ZAP-70 antibody |
|
STJ96295 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to ZAP-70. |
Anti-ZAP-70 antibody |
|
STJ96296 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to ZAP-70. |
Anti-ZAP-70 antibody |
|
STJ96297 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to ZAP-70. |
 Monoclonal ZAP-70 Antibody |
|
AMM03191G |
Leading Biology |
0.1ml |
EUR 484 |
|
Description: A Monoclonal antibody against Human ZAP-70. The antibodies are raised in Mouse. This antibody is applicable in WB, IP |
ZAP-70 Polyclonal Antibody |
|
46858-100ul |
SAB |
100ul |
EUR 252 |
ZAP-70 Polyclonal Antibody |
|
46858-50ul |
SAB |
50ul |
EUR 187 |
 Antibody) Zap-70 (Phospho-Tyr319) Antibody |
|
11159-100ul |
SAB |
100ul |
EUR 252 |
Zap-70 (Phospho-Tyr319) Antibody |
|
11159-50ul |
SAB |
50ul |
EUR 187 |
 Antibody) Zap-70 (Phospho-Tyr493) Antibody |
|
11160-100ul |
SAB |
100ul |
EUR 252 |
Zap-70 (Phospho-Tyr493) Antibody |
|
11160-50ul |
SAB |
50ul |
EUR 187 |
 Antibody) Zap-70 (Ab-319) Antibody |
|
21173-100ul |
SAB |
100ul |
EUR 252 |
Zap-70 (Ab-319) Antibody |
|
21173-50ul |
SAB |
50ul |
EUR 187 |
 Antibody) Zap-70 (Ab-493) Antibody |
|
21174-100ul |
SAB |
100ul |
EUR 252 |
Zap-70 (Ab-493) Antibody |
|
21174-50ul |
SAB |
50ul |
EUR 187 |
 Antibody) Phospho-ZAP-70 (Tyr319) Antibody |
|
AF3312 |
Affbiotech |
200ul |
EUR 304 |
|
Description: Phospho-ZAP-70 (Tyr319) Antibody detects endogenous levels of ZAP-70 only when phosphorylated at Tyrosine 319. |
 Antibody) Phospho-ZAP-70 (Tyr493) Antibody |
|
AF3313 |
Affbiotech |
200ul |
EUR 304 |
|
Description: Phospho-ZAP-70 (Tyr493) Antibody detects endogenous levels of ZAP-70 only when phosphorylated at Tyrosine 493. |
) Anti-Zap-70 Antibody (Monoclonal, 11H40) |
|
M00754 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Mouse Monoclonal Zap-70 Antibody (Monoclonal, 11H40). Validated in IHC, WB and tested in Human, Rat. |
 Polyclonal Antibody) ZAP-70 (phospho Tyr319) Polyclonal Antibody |
|
ES7528-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 (phospho Tyr319) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
ZAP-70 (phospho Tyr319) Polyclonal Antibody |
|
ES7528-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 (phospho Tyr319) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
 Polyclonal Antibody) ZAP-70 (phospho Tyr493) Polyclonal Antibody |
|
ES7529-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 (phospho Tyr493) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
ZAP-70 (phospho Tyr493) Polyclonal Antibody |
|
ES7529-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 (phospho Tyr493) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
 Polyclonal Antibody) ZAP-70 (phospho Tyr292) Polyclonal Antibody |
|
ES7530-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 (phospho Tyr292) from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
ZAP-70 (phospho Tyr292) Polyclonal Antibody |
|
ES7530-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 (phospho Tyr292) from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
 Polyclonal Antibody) ZAP-70 (phospho Tyr315) Polyclonal Antibody |
|
ES7531-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 (phospho Tyr315) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
ZAP-70 (phospho Tyr315) Polyclonal Antibody |
|
ES7531-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against ZAP-70 (phospho Tyr315) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
 Antibody) Anti-Zap-70 (Ab-319) Antibody |
|
A00754 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Zap-70 (Ab-319) Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat. |
ZAP-70 (phospho Tyr319) Polyclonal Antibody |
|
ABP56529-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr319) from Human, Mouse, Rat. This ZAP-70 phospho Tyr319) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y319 |
ZAP-70 (phospho Tyr319) Polyclonal Antibody |
|
ABP56529-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr319) from Human, Mouse, Rat. This ZAP-70 phospho Tyr319) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y319 |
ZAP-70 (phospho Tyr319) Polyclonal Antibody |
|
ABP56529-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr319) from Human, Mouse, Rat. This ZAP-70 phospho Tyr319) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y319 |
ZAP-70 (phospho Tyr493) Polyclonal Antibody |
|
ABP56530-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr493) from Human, Mouse, Rat. This ZAP-70 phospho Tyr493) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y493 |
ZAP-70 (phospho Tyr493) Polyclonal Antibody |
|
ABP56530-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr493) from Human, Mouse, Rat. This ZAP-70 phospho Tyr493) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y493 |
ZAP-70 (phospho Tyr493) Polyclonal Antibody |
|
ABP56530-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr493) from Human, Mouse, Rat. This ZAP-70 phospho Tyr493) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y493 |
ZAP-70 (phospho Tyr292) Polyclonal Antibody |
|
ABP56531-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr292) from Human, Mouse. This ZAP-70 phospho Tyr292) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y292 |
ZAP-70 (phospho Tyr292) Polyclonal Antibody |
|
ABP56531-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr292) from Human, Mouse. This ZAP-70 phospho Tyr292) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y292 |
ZAP-70 (phospho Tyr292) Polyclonal Antibody |
|
ABP56531-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr292) from Human, Mouse. This ZAP-70 phospho Tyr292) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y292 |
ZAP-70 (phospho Tyr315) Polyclonal Antibody |
|
ABP56532-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr315) from Human, Mouse. This ZAP-70 phospho Tyr315) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y315 |
ZAP-70 (phospho Tyr315) Polyclonal Antibody |
|
ABP56532-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr315) from Human, Mouse. This ZAP-70 phospho Tyr315) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y315 |
ZAP-70 (phospho Tyr315) Polyclonal Antibody |
|
ABP56532-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of ZAP-70 phospho Tyr315) from Human, Mouse. This ZAP-70 phospho Tyr315) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human ZAP-70 around the phosphorylation site of Y315 |
 antibody) Anti-Phospho-ZAP-70 (Y319) antibody |
|
STJ90436 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Phospho-ZAP-70 (Y319). |
 antibody) Anti-Phospho-ZAP-70 (Y493) antibody |
|
STJ90437 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Phospho-ZAP-70 (Y493). |
 antibody) Anti-Phospho-ZAP-70 (Y292) antibody |
|
STJ90483 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Phospho-ZAP-70 (Y292). |
 antibody) Anti-Phospho-ZAP-70 (Y315) antibody |
|
STJ90842 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Phospho-ZAP-70 (Y315). |
 Conjugated Antibody) Zap-70 (Ab-319) Conjugated Antibody |
|
C21173 |
SAB |
100ul |
EUR 397 |
 Antibody) Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody |
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20-abx127086 |
Abbexa |
|
|
|
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Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody |
|
abx036840-100ug |
Abbexa |
100 ug |
EUR 391 |
|
|
Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody |
|
abx036841-100ug |
Abbexa |
100 ug |
EUR 391 |
|
|
Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody |
|
20-abx001807 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 182.00
-
EUR 314.00
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
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Is the variety of novel chemical lessons of antibacterials restricted by the variety of broad spectrum drug targets; and (3) If true, then ought to we focus efforts on subgroups of pathogens like Gram unfavourable or optimistic micro organism solely, anaerobic micro organism or different group the place the vary of widespread important genes is probably going higher?. This assessment additionally supplies some examples of present drug targets that seem to flee the specter of mutation based mostly drug resistance, and supplies examples of some intermediate spectrum methods in addition to fashionable molecular and genomic approaches possible to enhance the chances of delivering 21st century medicines to fight multidrug resistant pathogens.
